Emphasis on Product (Cytotoxic Agents, EGFR Inhibitors, PD-1 Inhibitors, and Pipeline Drugs); End-Users (Hospitals, Clinics, and Others); and Region/Country
The PD-1 Resistant Head and Neck Cancer (HNC) market was valued at USD 1.5 billion in the year 2022 and is expected to grow at a strong CAGR of around 13% during the forecast period (2023-2030). PD-1-resistant head and neck cancer refers to a type of head and neck cancer that is resistant to treatment with immune checkpoint inhibitors, such as pembrolizumab (Keytruda) and nivolumab (Opdivo). These immune checkpoint inhibitors work by blocking the PD-1 protein, which is expressed on the surface of some immune cells and can suppress the immune system’s ability to recognize and attack cancer cells. The PD-1-resistant head and neck cancer market is expected to be a significant market due to the high prevalence of head and neck cancer and the need for effective treatment options for patients who are resistant to current therapies.
Some of the major players operating in the market include Ayala Pharmaceuticals; Amgen Inc.; AstraZeneca; Boehringer Ingelheim International GmbH; Bristol-Myers Squibb Company; Cel-Sci, GSK plc, Incyte; Merck KGaA; Novartis AG. Several M&As along with partnerships have been undertaken by these players to facilitate customers with hi-tech and innovative products/technologies.
Insights Presented in the Report
“Amongst product, the PD-1 inhibitors segment held a dominating share of the market in 2022”
Based on the product, the market is segmented into cytotoxic agents, EGFR inhibitors, PD-1 inhibitors, and pipeline drugs. Amongst these, the PD-1 inhibitors segment dominated the market in 2022. This is due to the high prevalence of head and neck cancer, the need for effective treatment options for patients who are resistant to current therapies, and the availability of several PD-1 inhibitors, such as pembrolizumab (Keytruda) and nivolumab (Opdivo), that have been approved for the treatment of head and neck cancer.
“Amongst End-users, clinics are expected to grow at a fast rate during the forecast period”
Based on end-users, the market is segmented into hospitals, clinics, and others. Among these, clinics are expected to grow at a fast rate during the forecast period. This is due to the increasing number of clinics that are offering immunotherapy treatments, including PD-1 inhibitors, for head and neck cancer patients who are resistant to current therapies.
“Asia Pacific dominated the PD-1 Resistant Head and Neck Cancer (HNC) market in 2022”
The Asia Pacific region is expected to be a significant market for PD-1 resistant head and neck cancer due to the high prevalence of head and neck cancer and the increasing awareness and understanding of the benefits of immunotherapy for the treatment of head and neck cancer. In recent years, the incidence of head and neck cancer has been increasing in many countries in the Asia Pacific region, and this trend is expected to continue in the coming years. This is due to a variety of factors, including increasing rates of tobacco and alcohol use, as well as a lack of awareness about the importance of early detection and treatment..
PD-1 Resistant Head and Neck Cancer (HNC) Market Report Coverage
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Research Methodology for the PD-1 Resistant Head and Neck Cancer (HNC) Market Analysis (2023-2030)
Analyzing the historical market, estimating the current market, and forecasting the future market of the global PD-1 resistant head and neck cancer (HNC) market were the three major steps undertaken to create and analyze the adoption of PD-1 resistant head and neck cancer (HNC) in major regions globally. Exhaustive secondary research was conducted to collect the historical market numbers and estimate the current market size. Secondly, to validate these insights, numerous findings and assumptions were taken into consideration. Moreover, exhaustive primary interviews were also conducted, with industry experts across the value chain of the global PD-1-resistant head and neck cancer (HNC) market. Post assumption and validation of market numbers through primary interviews, we employed a top-down/bottom-up approach to forecasting the complete market size. Thereafter, market breakdown and data triangulation methods were adopted to estimate and analyze the market size of segments and sub-segments of the industry pertains to. Detailed methodology is explained below:
Analysis of Historical Market Size
Step 1: In-Depth Study of Secondary Sources:
Detail secondary study was conducted to obtain the historical market size of the PD-1 resistant head and neck cancer (HNC) market through company internal sources such as annual reports & financial statements, performance presentations, press releases, etc., and external sources including journals, news & articles, government publications, competitor publications, sector reports, third-party database, and other credible publications.
Step 2: Market Segmentation:
After obtaining the historical market size of the PD-1-resistant head and neck cancer (HNC) market, we conducted a detailed secondary analysis to gather historical market insights and share for different segments & sub-segments for major regions. Major segments are included in the report as product and end-users. Further country-level analyses were conducted to evaluate the overall adoption of testing models in that region.
Step 3: Factor Analysis:
After acquiring the historical market size of different segments and sub-segments, we conducted a detailed factor analysis to estimate the current market size of the PD-1-resistant head and neck cancer (HNC) market. Further, we conducted factor analysis using dependent and independent variables such as product and end-users of the PD-1 resistant head and neck cancer (HNC) market. A thorough analysis was conducted for demand and supply-side scenarios considering top partnerships, mergers and acquisitions, business expansion, and product launches in the PD-1 resistant head and neck cancer (HNC) market sector across the globe.
Current Market Size Estimate & Forecast
Current Market Sizing: Based on actionable insights from the above 3 steps, we arrived at the current market size, key players in the global PD-1 resistant head and neck cancer (HNC) market, and market shares of the segments. All the required percentage shares split, and market breakdowns were determined using the above-mentioned secondary approach and were verified through primary interviews.
Estimation & Forecasting: For market estimation and forecast, weights were assigned to different factors including drivers & trends, restraints, and opportunities available for the stakeholders. After analyzing these factors, relevant forecasting techniques i.e., the top-down/bottom-up approach were applied to arrive at the market forecast for 2030 for different segments and sub-segments across the major markets globally. The research methodology adopted to estimate the market size encompasses:
Market Size and Share Validation
Primary Research: In-depth interviews were conducted with the Key Opinion Leaders (KOLs) including Top Level Executives (CXO/VPs, Sales Head, Marketing Head, Operational Head, Regional Head, Country Head, etc.) across major regions. Primary research findings were then summarized, and statistical analysis was performed to prove the stated hypothesis. Inputs from primary research were consolidated with secondary findings, hence turning information into actionable insights.
Split of Primary Participants in Different Regions
Market Engineering
The data triangulation technique was employed to complete the overall market estimation and to arrive at precise statistical numbers for each segment and sub-segment of the global PD-1 Resistant Head and Neck Cancer (HNC) market. data was split into several segments & sub-segments post studying various parameters and trends in the areas of the p product type, application, and distribution channel in the global PD-1 Resistant Head and Neck Cancer (HNC) market.
The main objective of the Global PD-1 Resistant Head and Neck Cancer (HNC) Market Study
The current & future market trends of the global PD-1 Resistant Head and Neck Cancer (HNC) market were pinpointed in the study. Investors can gain strategic insights to base their discretion for investments on the qualitative and quantitative analysis performed in the study. Current and future market trends determined the overall attractiveness of the market at a regional level, providing a platform for the industrial participant to exploit the untapped market to benefit from a first-mover advantage. Other quantitative goals of the studies include:
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