Protein Stability Analysis Market: Current Analysis and Forecast (2021-2027)


Emphasis on Product (Reagents and Assay Kits, Instruments, Consumables and Accessories, Software); Technique (Chromatography, Spectroscopy, Surface Plasma Resonance Imaging {SPRI}, Differential Scanning Calorimetry {DSC}, Differential Scanning Fluorimetry {DSF}, Others); End-User (Pharmaceutical and Biotechnological Companies, Contract Research Organizations, Academic and Government Institutes); and Regions/Country









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Research Methodology

Report Description

Protein Stability Analysis Market is anticipated display a CAGR of around 10% over the forecast period (2021-2027).
The global Protein Stability Analysis Market is expected to witness robust growth mainly due to the rising demand for protein stability analysis for the development and launch of new drugs by various biotechnology and pharmaceutical industry stakeholders. It is important various stakeholders in the industry to determine whether protein will be in its native folded conformation or a denatured (unfolded/misfolded) state. As, misfolded proteins denature easily and lose their structure and function. Thus, incorrect protein folding can lead to many human diseases such as Alzheimer’s disease, Huntington’s disease, and Parkinson’s disease. In addition, entry of new market players coupled with major biotech and pharma companies entering developing countries with a focus on the research and development of new drugs, is further expected to propel the market growth.

The ongoing COVID-19 pandemic across the world have had a tremendous impact on different spectra of society, the market for Protein Stability Analysis no less. Returning to some likeness of normalcy depends on continued safety measures, effective diagnostic testing, and widespread vaccination. Major players in the market have been at the center of the fight since the health crisis began, enabling research of the virus, ensuring the supply of critical kits and consumables, delivering the gold standard in testing, and supporting development, production and distribution of vaccines and treatments.

Insights Presented in the Report

“Amongst Product, Reagents and Kits segment dominated the market in 2020”

Based on Product, the Protein Stability Analysis Market is segmented into reagents and assay kits, instruments, consumables and accessories, and software. In 2020, reagents and assay kits category dominated the market and is expected to maintain its dominance throughout the forecast period. Major players in the market are focusing on new types of kits for the pharmaceutical and biotechnological companies as well as other end-users for performing stability analysis. For instance, PROTEOSTAT Thermal shift stability assay kit by Enzo Life Sciences Inc., includes a fluorescent dye which detects protein aggregation, so it can be used to monitor protein stability under systematic thermal stress conditions. It works over a wide temperature, pH and ionic strength range and compatible with commonly used buffers and excipients

“Amongst End-User, Pharmaceutical and biotechnological companies segment dominates the market”

Based on End Users, the market is bifurcated into Pharmaceutical and biotechnological companies, Contract research organizations, and academic and government institutes. The Pharmaceutical and biotechnological companies segment held the majority share in 2020, owing to rising focus on proteomics research and increasing production of biologics products. Furthermore, key players in the industry are focusing on mergers, acquisitions, and profitable partnerships, mainly to develop new products and gain competitive advantage. For instance, in 2020, Thermo Fisher Scientific Inc. acquired the biotechnology company, Qiagen (Germany). This acquisition will help Thermo Fisher Scientific to enhance its precision medicine portfolio through molecular diagnostics and improved life sciences solutions.

“Asia-Pacific is expected to witness highest growth during the forecast period”

For a better understanding of the demand of Protein Stability Analysis, the market is analyzed for major regions including North America (US, Canada, Rest of North America); Europe (Germany, UK, France, Italy, Rest of Europe); Asia-Pacific (China, India, Japan, South Korea, Rest of Asia-Pacific); and Rest of World. Currently, North America dominates the market; however, Asia-Pacific is expected to witness highest CAGR growth owing to rising healthcare expenditure in countries such as China, India, and other developing Asian countries. Some of the major players operating in the market include Thermo Fisher Scientific Inc., PerkinElmer Inc., Agilent Technologies Inc., KEP TECHNOLOGIES SA (SETARAM), Waters Corporation, Shimadzu Corporation, Enzo Biochem Inc., GE Healthcare, HORIBA Ltd., and Spectris PLC.

Reasons to buy this report:

  • The study includes market sizing and forecasting analysis validated by authenticated key industry experts
  • The report presents a quick review of overall industry performance at one glance
  • The report covers an in-depth analysis of prominent industry peers with a primary focus on key business financials, product portfolio, expansion strategies, and recent developments
  • Detailed examination of drivers, restraints, key trends, and opportunities prevailing in the industry
  • The study comprehensively covers the market across different segments
  • Deep dive regional level analysis of the industry

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1.1.    Market Definitions
1.2.    Limitation
1.3.    Stakeholders
1.4.    Currency used in Report
2.1.    Research Process of the Protein Stability Analysis Market
2.2.    Research Methodology of the Protein Stability Analysis Market
2.3.    Forecasting Method
2.4.    Respondent Profile
2.5.    Main Objective of the Protein Stability Analysis Market Study


7.1.    Reagents and Assay Kits
7.2.    Instruments
7.3.    Consumables and Accessories
7.4.    Software
8.1.    Chromatography
8.2.    Spectroscopy
8.3.    Surface Plasma Resonance Imaging (SPRI)
8.4.    Differential Scanning Calorimetry (DSC)
8.5.    Differential Scanning Fluorimetry (DSF)
8.6.    Others
9.1.    Pharmaceutical and Biotechnological Companies
9.2.    Contract Research Organizations
9.3.    Academic and Government Institutes
10.1.                     North America
10.1.1.    US
10.1.2.    Canada
10.1.3.    Rest of North America
10.2.                     Europe
10.2.1.    Germany
10.2.2.    UK
10.2.3.    France
10.2.4.    Italy
10.2.5.    Rest of Europe
10.3.                     Asia-Pacific
10.3.1.    China
10.3.2.    Japan
10.3.3.    India
10.3.4.    South Korea
10.3.5.    Rest of Asia-Pacific
10.4.                     Rest of World
11.1.                     Market Drivers
11.2.                     Market Challenges
11.3.                     Impact Analysis
15.1.                     Demand Side Analysis
15.2.                     Supply Side Analysis
15.2.1.    Top Product Launches
15.2.2.    Top Business Partnerships
15.2.3.    Top Business Expansions
15.2.4.    Top Merger and Acquisitions
17.1.                     Competitive Landscape
17.1.1.    Company Shares, By Revenue
18.1.                     Thermo Fisher Scientific Inc.
18.2.                     PerkinElmer Inc. 
18.3.                     Agilent Technologies Inc.
18.4.                     KEP TECHNOLOGIES SA (SETARAM)
18.5.                     Waters Corporation
18.6.                     Shimadzu Corporation
18.7.                     Enzo Biochem Inc.
18.8.                     GE Healthcare
18.9.                     HORIBA Ltd.
18.10.                  Spectris PLC

Research Methodology

Analyzing the historical market, estimation of the current market, and forecasting the future of the Protein Stability Analysis Market were the three major steps undertaken to create and analyze the demand and sales of Protein Stability Analysis across major regions globally. Exhaustive secondary research was conducted to collect the historical market numbers and estimate the current market size. Secondly, to validate these insights, numerous findings and assumptions were taken into consideration. Moreover, exhaustive primary interviews were conducted, with industry experts across the value chain of the industry. Post assumption and validation of market numbers through primary interviews, we employed a bottom-up approach to forecast the complete market size. Thereafter, market breakdown and data triangulation methods were adopted to estimate and analyze the market size of segments and sub-segments the industry pertains to. Detailed methodology is explained below.

Analysis of Historical Market Size

Step 1: In-Depth Study of Secondary Sources:

Detailed secondary study was conducted to obtain the historical market size of the Protein Stability Analysis through company internal sources such as annual report & financial statements, performance presentations, press releases, etc., and external sources including journals, news & articles, government publications, competitor publications, sector reports, third-party database, and other credible publications.

Step 2: Market Segmentation:

After obtaining the historical market size of the Protein Stability Analysis, we conducted a detailed secondary analysis to gather historical market insights and share for different segments & sub-segments for major regions. Major segments included in the report are product, technique, and end-user. Further regional level analyses were conducted to evaluate the overall demand of Protein Stability Analysis in global context.

Step 3: Factor Analysis:

After acquiring the historical market size of different segments and sub-segments, we conducted a detailed factor analysis to estimate the current market size. Further, we conducted factor analysis using dependent and independent variables such as growing vehicle ownership and technological advancement in the healthcare sector etc. Historical trends and their year-on-year impact on the market size and share was analyzed. Demand and supply side scenario was also thoroughly studied.

Current Market Size Estimate & Forecast

Current Market Sizing: Based on actionable insights from the above 3 steps, we arrived at the current market size, key players in the Market, and market shares of the segments and company. All the required percentage split, and market breakdowns were determined using the above-mentioned secondary approach and were verified through primary interviews.

Estimation & Forecasting: For market estimation and forecast, weights were assigned to different factors including drivers & trends, restraints, and opportunities available for the stakeholders. After analyzing these factors, relevant forecasting techniques i.e., bottom-up approach was applied to arrive at the market forecast to 2027 for different segments and subsegments across the major regions globally. The research methodology adopted to estimate the market size encompasses:

  • The industry’s market size, in terms of value (US$) and the demand of Protein Stability Analysis across the major regions globally
  • All percentage shares, splits, and breakdowns of market segments and sub-segments
  • Key players in the Protein Stability Analysis Market in terms of products offered. Also, the growth strategies adopted by these players to compete in the fast-growing market.

Market Size and Share Validation

Primary Research: In-depth interviews were conducted with the Key Opinion Leaders (KOLs) including Top Level Executives (CXO/VPs, Sales Head, Marketing Head, Operational Head, and Regional Head, Country Head, etc.) across major countries. Primary research findings were then summarized, and statistical analysis was performed to prove the stated hypothesis. Inputs from primary research were consolidated with secondary findings, hence turning information into actionable insights.

Split of Primary Participants in Different Regions

Market Engineering

Data triangulation technique was employed to complete the overall market estimation and to arrive at precise statistical numbers of each segment and sub-segment of the Protein Stability Analysis market. Data was split into several segments & sub-segments post studying various parameters and trends in the areas of product type, technique, end-user, and regions.

The main objective of the Protein Stability Analysis Market Study

The current & future market trends of the Protein Stability Analysis Market are pinpointed in the study. Investors can gain strategic insights to base their discretion for investments from the qualitative and quantitative analysis performed in the study. Current and future market trends would determine the overall attractiveness of the market at a regional level, providing a platform for the industrial participant to exploit the untapped market to benefit as a first-mover advantage. Other quantitative goals of the studies include:

  • Analyze the current and forecast market size of Protein Stability Analysis in terms of value (USD). Also, analyze the current and forecast market size of different segments and sub-segments of the industry
  • Segments in the study include product type, technique, end-user, and regions
  • Defined analysis of the regulatory framework for the Protein Stability Analysis industry
  • Analyze the value chain involved with the presence of various intermediaries, along with analyzing customer and competitor behaviors pertaining to the industry
  • Analyze the current and forecast market size of the Protein Stability Analysis across the globe. Major regions analyzed in the report include North America (US, Canada, Rest of North America); Europe (Germany, UK, France, Italy, Rest of Europe); Asia-Pacific (China, India, Japan, South Korea, Rest of Asia-Pacific); and Rest of World. Define and analyze the competitive landscape of the Protein Stability Analysis sector and the growth strategies adopted by the market players to sustain in the fast-growing market

Deep dive regional level analysis of the industry