Therapeutic Plasma Exchange Market: Current Analysis and Forecast (2025-2033)

Global Therapeutic Plasma Exchange Market Size & Forecast

The global therapeutic plasma exchange market was valued at USD 1,451 million in 2024 and is expected to grow at a strong CAGR of around 7.98% during the forecast period (2025-2033F), driven by rising demand for advanced plasma exchange procedures and increasing prevalence of autoimmune diseases worldwide.

Therapeutic Plasma Exchange Market Analysis

Therapeutic plasma exchange (TPE) is an extracorporeal procedure of blood purification that is applied to treat patients with a range of conditions. TPE is a relatively common treatment modality nowadays. It shows positive clinical outcomes in the management of Guillain-Barré syndrome, thrombotic thrombocytopenic purpura (TTP), myasthenia gravis, and Goodpasture syndrome.

Global Therapeutic Plasma Exchange Market Trends

This section discusses the key market trends that are influencing the various segments of the global Therapeutic Plasma Exchange market, as found by our team of research experts.

Growing Adoption of Portable and Compact TPE Devices: The Latest Trend in the TPE Market

Increasing portability and compact size of therapeutic plasma exchange (TPE) machines is becoming a market trend in the global TPE market due to the increased demand for point-of-care solutions and the need to make therapeutic plasma exchange accessible in critical care environments and in rural areas. Some of the benefits of these devices are that they require less time to set up, are more mobile, require less space, and can be used in ICUs, at-home treatment, and in emergency treatment settings.

Therapeutic Plasma Exchange Industry Segmentation

This section provides an analysis of the key trends in each segment of the global therapeutic plasma exchange market report, along with forecasts at the global, regional, and country levels for 2025-2033.

The Devices Segment Dominates the Global Therapeutic Plasma Exchange Market

Based on the product category, the market is categorized into devices and consumables. Out of these, the devices currently hold the maximum market share in the therapeutic plasma exchange market, primarily due to their high cost, long lifespan, and repeated use in various treatment sessions, which in turn significantly increases revenue. However, the consumables segment is expected to witness the fastest growth in the future, due to their frequent application in every procedure, a surge in high volumes of procedures, and the increasing implementation of single-use kits to minimize the risk of infection.

The Neurological Disorders Segment Dominates the Global Therapeutic Plasma Exchange Market.

Based on the indication category, the market is segmented into neurological disorders, hematological disorders, renal disorders, metabolic disorders, and other indications. Among these, neurological disorders hold the maximum market share, owing to the high rate of diseases, like myasthenia Gravis, Guillain-Barré syndrome, and multiple sclerosis, in which TPE is commonly used as a treatment measure. However, the renal disorders segment is expected to witness the fastest growth in the coming years, owing to rising cases of renal ailments and the broad utilization of TPE in the management of diseases such as Goodpasture syndrome and antibody-mediated transplant rejection, backed by growing clinical trials and treatment authorizations.

The Asia-Pacific region shows the Fastest Growth in the Global Therapeutic Plasma Exchange Market.

The Asia-Pacific region is expected to grow significantly in the future because of the growing number of patients in this region, increasing rates of chronic and autoimmune illnesses, and an increasing need for progressive medication facilities. The healthcare systems are rapidly improving, investment in medical technology is on the rise, and access to specialized therapy is also increasing, leading to the growth of the market. Additionally, the affordability of therapies, the growing government healthcare actions, and the intensifying awareness of both medical practitioners and patients have further boosted the adoption rate. Asian countries such as China, Japan, and India are leading the development of the region since they have a higher volume of procedures and increased investments in the healthcare industry.

India held a Dominant share of the Asia-Pacific Therapeutic Plasma Exchange Market in 2024

In 2024, the Asia‑Pacific therapeutic plasma exchange (TPE) market is dominated by India because it has a huge patient base, there is a sharp growth in autoimmune, neurological, and metabolic disorders, and there is the availability of cost‑effective treatment infrastructure. For instance, according to the American Journal of Emergency Medicine, worldwide, there are approximately 100,000 new cases of GBS annually. The disease has the highest incidence in Bangladesh and India, with an incidence of 2.5 adult cases per 100,000 person-years and 3.25 cases per 100,000 person-years in pediatric patients. Additionally, there is a tendency for the incidence to increase by 20% for every 10-year rise in age. Domestic and multinational companies, such as Fresenius Kabi and Gambro BCT, have expanded their distribution systems to tier-2 cities, resulting in enhanced accessibility. Moreover, collaboration and partnership activities, along with initiatives to donate plasma, are the factors resulting in a large volume of procedures. All this strengthened India's market stronghold.

Therapeutic Plasma Exchange Industry Competitive Landscape

The global therapeutic plasma exchange market is competitive, with several global and international market players. The key players are adopting different growth strategies to enhance their market presence, such as partnerships, agreements, collaborations, geographical expansions, and mergers and acquisitions.

Top Therapeutic Plasma Exchange Companies

Some of the major players in the market are Nikkiso Co., Ltd., Miltenyi Biotec B.V. & Co. KG, Vantive Health LLC, Fresenius Medical Care, Asahi Kasei Corporation, Terumo Corporation, B. Braun SE, Sb-Kawasumi Laboratories, Inc. (Sumitomo Bakelite Co., Ltd.), Maco Pharma, and Octapharma AG.

Recent Developments in the Therapeutic Plasma Exchange Market

• In May 2025, Terumo Blood and Cell Technologies (Terumo BCT) announced that Join Parachute had implemented its Rika™ Plasma Donation System, which is a next-generation platform aimed at improving plasma collection efficiency and donor comfort. The system’s iNomi™ Nomogram allowed personalized plasma collection of up to 1,000 mL in under 35 minutes, with less than 200 mL of blood cells outside the body at any time.

• In November 2024, Terumo Blood and Cell Technologies (Terumo BCT) launched its new Global Therapy Innovations business unit to advance care standards across the patient journey, with a strong focus on therapeutic plasma exchange and other apheresis-based treatments. Led by Veerle d'Haenens, the unit aims to integrate disease expertise and develop coordinated therapy systems, particularly in areas like sickle cell disease, where therapeutic apheresis plays a critical role.

Global Therapeutic Plasma Exchange Market Report Coverage

Reasons to Buy the Therapeutic Plasma Exchange Market Report:

• The study includes market sizing and forecasting analysis confirmed by authenticated key industry experts.

• The report briefly reviews overall industry performance at a glance.

• The report covers an in-depth analysis of prominent industry peers, primarily focusing on key business financials, type portfolios, expansion strategies, and recent developments.

• Detailed examination of drivers, restraints, key trends, and opportunities prevailing in the industry.

• The study comprehensively covers the market across different segments.

• Deep dive regional level analysis of the industry.

Customization Options:

The global Therapeutic Plasma Exchange market can further be customized as per the requirements or any other market segment. Besides this, UnivDatos understands that you may have your own business needs; hence, feel free to contact us to get a report that completely suits your requirements.